Sperm Chromatin Dispersion Test (SCD)
evaluating male fertility (concentration, motility and morphology) but it does not give any information about the percentage of spermatozoa with DNA fragmentation. The integrity of sperm DNA can be disturbed as a result of exposure to chemicals, smoking, high temperature, free radicals, produced as a result of normal metabolism, and other factors. A high percentage of DNA fragmentation is associated with a lower fertilization rate, worse embryo quality and higher incidence of miscarriage.
Indications for the SCD test
The test is recommended for patients with deviations in the main sperm parameters as well as for those with normal parameters who have undergone several unsuccessful IVF cycles or who suffer from unexplained infertility.